Let’s break down the real-world genetic hurdles and the speculative “fixes” the community often plays with. In reality, our size is capped by the square-cube law. If you simply scaled a 5'6" woman to 150 feet, her bone cross-section would increase by the square of the scale factor, but her volume (and weight) would increase by the cube. The result? Her femurs would shatter under her own mass, and her heart couldn't pump blood up to her brain.
Unpacking the Code: The Science (and Pseudoscience) Behind GiantessGenetics
— Authored for the speculative biology and size fantasy community.